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SciMed/Genetics & Genome
Epigenetic Control Can Reverse Honeybee Behavior Patterns
TS-Si News Service
Monday, 17 September 2012
Baltimore, MD, USA. Complex, reversible behavioral patterns in bees — and perhaps other animals — link to reversible chemical tags on genes, according to a new study.

DNA methylation patterns differentiate nurse and forager honeybees, reports this study. Further, reverting foragers back to nurses reestablishes nurse-associated methylation levels for a majority of genes.


Guthrie Cards Join Modern Epigenomic Information Resources
TS-Si News Service
Sunday, 26 August 2012
Cold Spring Harbor, NY, USA. Epigenetic information from spots of a newborn's blood on filter paper has provided a powerful retrospective view of the epigenome at birth.

The Guthrie test, originally devised to detect phenylketonuria, a disorder of amino acid metabolism, has become so routine over the last 50 years that since 2000, more than 90% of newborns in the United States have had their blood archived for analysis.

Genetic Markers for Estrogen and Testosterone Level Regulation
TS-Si News Service
Monday, 23 July 2012
Exeter, Devon, UK. A research study has identified genetic markers that influence a protein involved in regulating estrogen and testosterone levels in the bloodstream.

The results also reveal that some of the genetic markers for this protein are near genes related to liver function, metabolism and type 2 diabetes, demonstrating an important genetic connection between the metabolic and reproductive systems in men and women.

Multiple Sperm Cells Sequenced From One Human Male
TS-Si News Service
Saturday, 21 July 2012
Stanford, CA, USA. Researchers have sequenced the genomes of 91 sperm from one human male, providing a glimpse into naturally occurring genetic variation in one individual.

Stanford University researchers are the first to report the whole-genome sequence of a human gamete — the only cells that become a child and through which parents pass on physical traits.

Prenatal Environment Helps Define Newborn Epigenetic Profile
TS-Si News Service
Monday, 16 July 2012
Parkville, Australia. For the first time, researchers have shown that the prenatal environment helps define the newborn epigenetic profile across the genome.

A study of the differences between human twins at birth highlight the importance of chemical modifications to DNA in the intrauterine environment, molding the human epigenome.

Bioethics Slam on Testosterone Testing for Female Olympic Athletes
TS-Si News Service
Thursday, 14 June 2012
Stanford, CA, USA. Proposed testosterone testing policies for female Olympic athletes could discriminate against women who may not meet traditional notions of femininity.

A Stanford University School of Medicine bioethicist and her colleagues say that the policies distort the scientific evidence on the relationship between testosterone, sex and athletic performance.

TS-Si News Service
Tuesday, 12 June 2012
TS-Si News Service
Friday, 08 June 2012
Test Detects Chromosome Number Anomalies In Human Eggs
TS-Si News Service
Sunday, 03 June 2012
Oxford, UK. An in vitro fertilization (IVF) test detects chromosome number anomalies (aneuploidy), a finding with longer-term implications for human reproduction studies.

Only a comparatively few oocytes (eggs) per IVF treatment cycle are able to produce a pregnancy because many eggs have chromosomal irregularities. Misidentification can increase the risk of aneuploidy, leading to miscarriage and Down syndrome.

Sex and Sweeping Out the Gene Pool
TS-Si News Service
Friday, 01 June 2012
Houghton, MI, USA. Sexual reproduction confers the significant evolutionary advantage of new genetic combinations, strengthening an organism's ability to adapt.

Sexual reproduction can sweep mutations out of the gene pool more quickly by shuffling genetic material with each generation, increasing the likelihood of new genetic combinations that help organisms adapt to their environment. However, there had been no direct empirical evidence to support the advantage of new genetic combinations.

Genomic Survey Shows Supposedly Rare Genetic Variants Surprisingly Common
TS-Si News Service
Sunday, 20 May 2012
Los Angeles, CA, USA. A large survey of human genetic variation found one genetic variant for every 17 bases, a dramatically higher rate than expected by the investigators.

The procedures used for the study have implications for tracing and understanding non-disease states, as well as the degree to which human variations of any type are common in human populations.

Genomic Dark Matter Infected With Ancient Viral DNA
TS-Si News Service
Wednesday, 25 April 2012
New York, NY, USA. Ninety percent of every mammal's genome is dark matter harboring ancient viral DNA that infected our ancestors from as far back as the age of the dinosaurs.

Scientists have uncovered clues as to how our genomes became riddled with viruses, revealing important new information.

Chromosome Yarns Organize Groups of Genes and Regulatory Elements
TS-Si News Service
Wednesday, 11 April 2012
Worcester, MA, USA. A chromosome layer folds into contiguous yarns that harbor groups of genes and regulatory elements, enabling contact for coordinated development work.

This is a new layer in the complex organization of chromosomes, the molecular basis of genetic heredity. Even though chromosomes have remain largely enigmatic since biologist Walther Flemming discovered them in 1882, recent research has begun to unravel some of their mysteries.

TS-Si News Service
Sunday, 11 March 2012
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Thursday, 08 March 2012
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Friday, 02 March 2012
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Tuesday, 28 February 2012
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Tuesday, 21 February 2012
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Monday, 20 February 2012
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Monday, 13 February 2012
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Friday, 10 February 2012
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Tuesday, 07 February 2012
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Sunday, 22 January 2012